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Efficacy and safety of ocrelizumab in primary progressive multiple sclerosis, including older patients and those with more advanced disease (ORATORIO-HAND): a multicentre, double-blind, randomised, placebo-controlled, phase 3b study

Author:

Gavin Giovannoni,Laura Airas,Riley Bove,Gary R Cutter,Maciej Czarnecki,Jelena Drulovic,Jeremy Hobart,Jens Kuhle,Xavier Montalban,Krzysztof W Selmaj,Carmen Tur,Jerry S Wolinsky,Anna Baldinotti,Ulrike Bonati,Licinio Craveiro,Caroline Giacobino et al.

Publication:

The Lancet

Publisher:

Elsevier

Date:

30 May–5 June 2026

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