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Structural Basis for Binding and Selectivity of Antimalarial and Anticancer Ethylenediamine Inhibitors to Protein Farnesyltransferase

Author:

Michael A. Hast,Steven Fletcher,Christopher G. Cummings,Erin E. Pusateri,Michelle A. Blaskovich,Kasey Rivas,Michael H. Gelb,Wesley C. Van Voorhis,Said M. Sebti,Andrew D. Hamilton,Lorena S. Beese

Publication:

Chemistry & Biology

Publisher:

Elsevier

Date:

27 February 2009

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