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Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450

Author:

C. Nicholas Hodge,Paul E. Aldrich,Lee T. Bacheler,Chong-Hwan Chang,Charles J. Eyermann,Sena Garber,Mary Grubb,David A. Jackson,Prabharkar K. Jadhav,Bruce Korant,Patrick Y.S. Lam,Michael B. Maurin,James L. Meek,Michael J. Otto,Marlene M. Rayner et al.

Publication:

Chemistry & Biology

Publisher:

Elsevier

Date:

April 1996

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