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Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Shows Rapid Primary Engraftment with CD33-Negative Hematopoiesis in Patients with High-Risk Acute Myeloid Leukemia (AML) and Avoids Hematopoietic Toxicity during Gemtuzumab Ozogamicin (GO) Maintenance Post-Hematopoietic Cell Transplant (HCT).

Author:

John F. DiPersio,Brenda Cooper,Hyung C. Suh,Divya Koura,Léa Bernard,Nirali N. Shah,Roland B. Walter,Miguel-Angel Perales,Markus Y. Mapara,Roni Tamari,Michael Loken,Kyle Breitschwerdt,Sritama Nath,Glen D Raffel,Guenther Koehne

Publication:

Transplantation and Cellular Therapy

Publisher:

Elsevier

Date:

February 2024

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