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A new approach to synthesis of vinblastine analogs. Addition of organozinc reagents to the dihydropyridinium ion generated by fragmentative coupling to catharanthine and vindoline.

Author:

Richard J. Sundberg,Jean-Luc Bettiol,Kumar G. Gadamasetti,Mary Marshalla,Laurie Kelsh

Publication:

Bioorganic & Medicinal Chemistry Letters

Publisher:

Elsevier

Date:

25 August 1994

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