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Pyridinyl ring defines a noncanonical P1-S1 axis that revamps inhibitor design against coronaviral main proteases

Author:

Gan Luo,Baisen Zhong,Gang Wang,Lu Zheng,Chongbing Liao,Jie Rao,Man Luo,Junjie Zhang,Jue Zhang,Xihui Gao,Wuyuan Lu

Publication:

Cell Reports Physical Science

Publisher:

Elsevier

Date:

Available online 15 June 2026

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