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Total neoadjuvant treatment with short-course radiotherapy followed by sintilimab plus capecitabine–oxaliplatin versus short-course radiotherapy followed by capecitabine–oxaliplatin in patients with locally advanced rectal cancer (SPRING-01): a single-centre, open-label, phase 2, randomised controlled trial

Author:

Feng Tian,Honghai Dai,Dan Sha,Yuanzi Yu,Haiyan Jing,Cong Sun,Liang Shang,Yubo Liu,Renxiang Feng,Jun Li,Hongjun Liu,Yuezhi Chen,Yulong Shi,Jinshen Wang,Hongqing Zhuo,Xiaoqiao Zhang,Guodong Lian,Wei Chong,Hao Chen,Zhe Yang,Leping Li,Changqing Jing

Publication:

The Lancet Oncology

Publisher:

Elsevier

Date:

August 2025

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